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Chondrogenic differentiation of human bone marrow MSCs in osteochondral implants under kinematic mechanical load is dependent on the underlying osteo component
Chondrogenic models utilizing human mesenchymal stromal cells (hMSCs) are often simplistic, with a single cell type and the absence of mechanical stimulation. Considering the articulating joint as an organ it would be beneficial to include more complex stimulation. Within this study we applied clini...
Autores principales: | Monaco, Graziana, Qawasmi, Feras, El Haj, Alicia J., Forsyth, Nicolas R., Stoddart, Martin J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9622941/ https://www.ncbi.nlm.nih.gov/pubmed/36329702 http://dx.doi.org/10.3389/fbioe.2022.998774 |
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