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Hypoxia-driven metabolic reprogramming of adipocytes fuels cancer cell proliferation

OBJECTIVE: Obesity increases the risk of certain cancers, especially tumours that reside close to adipose tissue (breast and ovarian metastasis in the omentum). The obesogenic and tumour micro-environment share a common pathogenic feature, oxygen deprivation (hypoxia). Here we test how hypoxia chang...

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Detalles Bibliográficos
Autores principales: Aird, R., Wills, J., Roby, K. F., Bénézech, C., Stimson, R. H., Wabitsch, M., Pollard, J. W., Finch, A., Michailidou, Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9623062/
https://www.ncbi.nlm.nih.gov/pubmed/36329893
http://dx.doi.org/10.3389/fendo.2022.989523