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A bone-based 3D scaffold as an in-vitro model of microenvironment–DLBCL lymphoma cell interaction

About 30% of patients with diffuse large B-cell lymphoma (DLBCL) relapse or exhibit refractory disease (r/r DLBCL) after first-line immunochemotherapy. Bone marrow (BM) involvement confers a dismal prognosis at diagnosis, likely due to the interaction between neoplastic cells and a complex tumor mic...

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Detalles Bibliográficos
Autores principales: Ceccato, Jessica, Piazza, Maria, Pizzi, Marco, Manni, Sabrina, Piazza, Francesco, Caputo, Ilaria, Cinetto, Francesco, Pisoni, Lorena, Trojan, Diletta, Scarpa, Riccardo, Zambello, Renato, Tos, Angelo Paolo Dei, Trentin, Livio, Semenzato, Gianpietro, Vianello, Fabrizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9623125/
https://www.ncbi.nlm.nih.gov/pubmed/36330473
http://dx.doi.org/10.3389/fonc.2022.947823