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V-ATPase/TORC1-mediated ATFS-1 translation directs mitochondrial UPR activation in C. elegans

To adapt mitochondrial function to the ever-changing intra- and extracellular environment, multiple mitochondrial stress response (MSR) pathways, including the mitochondrial unfolded protein response (UPR(mt)), have evolved. However, how the mitochondrial stress signal is sensed and relayed to UPR(m...

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Detalles Bibliográficos
Autores principales: Li, Terytty Yang, Gao, Arwen W., Li, Xiaoxu, Li, Hao, Liu, Yasmine J., Lalou, Amelia, Neelagandan, Nagammal, Naef, Felix, Schoonjans, Kristina, Auwerx, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9623136/
https://www.ncbi.nlm.nih.gov/pubmed/36314986
http://dx.doi.org/10.1083/jcb.202205045