Cargando…

Systematic analysis of the effects of genetic variants on chromatin accessibility to decipher functional variants in non-coding regions

Genome-wide association study (GWAS) has identified thousands of single nucleotide polymorphisms (SNPs) associated with complex diseases and traits. However, deciphering the functions of these SNPs still faces challenges. Recent studies have shown that SNPs could alter chromatin accessibility and re...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Dongyang, Wu, Xiaohong, Jiang, Guanghui, Yang, Jianye, Yu, Zhanhui, Yang, Yanbo, Yang, Wenqian, Niu, Xiaohui, Tang, Ke, Gong, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9623183/
https://www.ncbi.nlm.nih.gov/pubmed/36330496
http://dx.doi.org/10.3389/fonc.2022.1035855