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Systematic analysis of the effects of genetic variants on chromatin accessibility to decipher functional variants in non-coding regions
Genome-wide association study (GWAS) has identified thousands of single nucleotide polymorphisms (SNPs) associated with complex diseases and traits. However, deciphering the functions of these SNPs still faces challenges. Recent studies have shown that SNPs could alter chromatin accessibility and re...
Autores principales: | Wang, Dongyang, Wu, Xiaohong, Jiang, Guanghui, Yang, Jianye, Yu, Zhanhui, Yang, Yanbo, Yang, Wenqian, Niu, Xiaohui, Tang, Ke, Gong, Jing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9623183/ https://www.ncbi.nlm.nih.gov/pubmed/36330496 http://dx.doi.org/10.3389/fonc.2022.1035855 |
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