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A phase II study of buparlisib in relapsed or refractory thymomas

PURPOSE: To investigate the efficacy and safety of buparlisib, an oral pan-PI3K inhibitor, in relapsed or refractory thymomas. METHODS: This was a single center, single arm, open label phase II trial of buparlisib in patients with recurrent thymoma who have progressed after at least one prior line o...

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Detalles Bibliográficos
Autores principales: Abu Zaid, Mohammad I., Radovich, Milan, Althouse, Sandra, Liu, Hao, Spittler, Aaron J., Solzak, Jeffrey, Badve, Sunil, Loehrer, Patrick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9623263/
https://www.ncbi.nlm.nih.gov/pubmed/36330484
http://dx.doi.org/10.3389/fonc.2022.891383