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T-BET drives the conversion of human type 3 innate lymphoid cells into functional NK cells

Type 3 innate lymphoid cells (ILC3s) are characterized by RORγt expression and they produce IL-22 upon activation. ILC3s play a role in maintenance of barrier integrity in the intestine. Under inflammatory conditions, the ILC composition of the mucosal tissues is altered due to a high degree of plas...

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Detalles Bibliográficos
Autores principales: Kiekens, Laura, Wahlen, Sigrid, Persyn, Eva, De Vos, Zenzi, Taghon, Tom, Vandekerckhove, Bart, Leclercq, Georges
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9623292/
https://www.ncbi.nlm.nih.gov/pubmed/36330517
http://dx.doi.org/10.3389/fimmu.2022.975778