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T-BET drives the conversion of human type 3 innate lymphoid cells into functional NK cells
Type 3 innate lymphoid cells (ILC3s) are characterized by RORγt expression and they produce IL-22 upon activation. ILC3s play a role in maintenance of barrier integrity in the intestine. Under inflammatory conditions, the ILC composition of the mucosal tissues is altered due to a high degree of plas...
Autores principales: | Kiekens, Laura, Wahlen, Sigrid, Persyn, Eva, De Vos, Zenzi, Taghon, Tom, Vandekerckhove, Bart, Leclercq, Georges |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9623292/ https://www.ncbi.nlm.nih.gov/pubmed/36330517 http://dx.doi.org/10.3389/fimmu.2022.975778 |
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