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Lactate from the tumor microenvironment - A key obstacle in NK cell-based immunotherapies

Recent findings about the new roles of lactate have changed our understanding of this end product of glycolysis or fermentation that was once considered only a waste product. It is now well accepted that lactate acts as a signaling molecule and fuel source for cancer cells in a glucose-restricted en...

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Detalles Bibliográficos
Autores principales: Jedlička, Marek, Feglarová, Tereza, Janstová, Lucie, Hortová-Kohoutková, Marcela, Frič, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9623302/
https://www.ncbi.nlm.nih.gov/pubmed/36330529
http://dx.doi.org/10.3389/fimmu.2022.932055