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Proanthocyanidins-loaded complex coacervates-based drug delivery attenuates oral squamous cell carcinoma cells metastatic potential through down-regulating the Akt signaling pathway

Oral cancer, constituted up to 90% by squamous cell carcinomas, is a significant health burden globally. Grape seed proanthocyanidins (PA) have been suggested as a potential chemopreventive agent for oral cancer. However, their efficacy can be restricted due to the low bioavailability and bioaccessi...

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Detalles Bibliográficos
Autores principales: Liu, Ju-Fang, Wee, Yinshen, Luo, Shen-Dean, Chang, Shwu-Fen, Jia, Shihai, Feng, Sheng-Wei, Huang, Huei-Mei, Lin, Jiann-Her, Wang, Ching-Shuen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9623311/
https://www.ncbi.nlm.nih.gov/pubmed/36330492
http://dx.doi.org/10.3389/fonc.2022.1001126