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Multiple-dose up-titration study to evaluate the pharmacokinetics, safety and antitumor activity of apatinib in advanced gastric adenocarcinoma

BACKGROUND AND PURPOSE: The objective of this study was to investigate the pharmacokinetics, safety, and antitumor activity of apatinib, a vascular endothelial growth factor receptor 2 inhibitor, in advanced gastric adenocarcinoma or gastroesophageal junction adenocarcinoma and evaluate the effect o...

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Detalles Bibliográficos
Autores principales: Wang, Yonggang, Wang, Chang, Zhang, Yanqiao, Hao, Jiqing, Yang, Nong, Wang, Jvfeng, Peng, Min, Liu, Tianshu, Zhang, Guifang, Zhan, Xianbao, Zeng, Shan, Zhang, Yifan, Gao, Yong, Yao, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9623328/
https://www.ncbi.nlm.nih.gov/pubmed/36330490
http://dx.doi.org/10.3389/fonc.2022.876899