Clonal lineage tracing reveals mechanisms skewing CD8(+) T cell fate decisions in chronic infection

Although recent evidence demonstrates heterogeneity among CD8(+) T cells during chronic infection, developmental relationships and mechanisms underlying their fate decisions remain incompletely understood. Using single-cell RNA and TCR sequencing, we traced the clonal expansion and differentiation o...

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Detalles Bibliográficos
Autores principales: Kasmani, Moujtaba Y., Zander, Ryan, Chung, H. Kay, Chen, Yao, Khatun, Achia, Damo, Martina, Topchyan, Paytsar, Johnson, Kaitlin E., Levashova, Darya, Burns, Robert, Lorenz, Ulrike M., Tarakanova, Vera L., Joshi, Nikhil S., Kaech, Susan M., Cui, Weiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9623343/
https://www.ncbi.nlm.nih.gov/pubmed/36315049
http://dx.doi.org/10.1084/jem.20220679

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9623343/
https://www.ncbi.nlm.nih.gov/pubmed/36315049
http://dx.doi.org/10.1084/jem.20220679

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