P38 kinases mediate NLRP1 inflammasome activation after ribotoxic stress response and virus infection

Inflammasomes integrate cytosolic evidence of infection or damage to mount inflammatory responses. The inflammasome sensor NLRP1 is expressed in human keratinocytes and coordinates inflammation in the skin. We found that diverse stress signals induce human NLRP1 inflammasome assembly by activating M...

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Detalles Bibliográficos
Autores principales: Jenster, Lea-Marie, Lange, Karl-Elmar, Normann, Sabine, vom Hemdt, Anja, Wuerth, Jennifer D., Schiffelers, Lisa D.J., Tesfamariam, Yonas M., Gohr, Florian N., Klein, Laura, Kaltheuner, Ines H., Ebner, Stefan, Lapp, Dorothee J., Mayer, Jacob, Moecking, Jonas, Ploegh, Hidde L., Latz, Eicke, Meissner, Felix, Geyer, Matthias, Kümmerer, Beate M., Schmidt, Florian I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9623368/
https://www.ncbi.nlm.nih.gov/pubmed/36315050
http://dx.doi.org/10.1084/jem.20220837

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9623368/
https://www.ncbi.nlm.nih.gov/pubmed/36315050
http://dx.doi.org/10.1084/jem.20220837

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