Pre-infection antiviral innate immunity contributes to sex differences in SARS-CoV-2 infection

Male sex is a major risk factor for SARS-CoV-2 infection severity. To understand the basis for this sex difference, we studied SARS-CoV-2 infection in a young adult cohort of United States Marine recruits. Among 2,641 male and 244 female unvaccinated and seronegative recruits studied longitudinally,...

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Detalles Bibliográficos
Autores principales: Sauerwald, Natalie, Zhang, Zijun, Ramos, Irene, Nair, Venugopalan D., Soares-Schanoski, Alessandra, Ge, Yongchao, Mao, Weiguang, Alshammary, Hala, Gonzalez-Reiche, Ana S., van de Guchte, Adriana, Goforth, Carl W., Lizewski, Rhonda A., Lizewski, Stephen E., Amper, Mary Anne S., Vasoya, Mital, Seenarine, Nitish, Guevara, Kristy, Marjanovic, Nada, Miller, Clare M., Nudelman, German, Schilling, Megan A., Sealfon, Rachel S.G., Termini, Michael S., Vangeti, Sindhu, Weir, Dawn L., Zaslavsky, Elena, Chikina, Maria, Wu, Ying Nian, Van Bakel, Harm, Letizia, Andrew G., Sealfon, Stuart C., Troyanskaya, Olga G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Inc. 2022
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9623453/
https://www.ncbi.nlm.nih.gov/pubmed/36323307
http://dx.doi.org/10.1016/j.cels.2022.10.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9623453/
https://www.ncbi.nlm.nih.gov/pubmed/36323307
http://dx.doi.org/10.1016/j.cels.2022.10.005

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