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Quorum-sensing- and type VI secretion-mediated spatiotemporal cell death drives genetic diversity in Vibrio cholera

Bacterial colonies composed of genetically identical individuals can diversify to yield variant cells with distinct genotypes. Variant outgrowth manifests as sectors. Here, we show that Type VI secretion system (T6SS)-driven cell death in Vibrio cholerae colonies imposes a selective pressure for the...

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Detalles Bibliográficos
Autores principales: Mashruwala, Ameya A., Qin, Boyang, Bassler, Bonnie L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9623500/
https://www.ncbi.nlm.nih.gov/pubmed/36167071
http://dx.doi.org/10.1016/j.cell.2022.09.003