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A systemic cell stress signal confers neuronal resilience toward oxidative stress in a Hedgehog-dependent manner

Cells possess several conserved adaptive mechanisms to respond to stress. Stress signaling is initiated to reestablish cellular homeostasis, but its effects on the tissue or systemic levels are far less understood. We report that the secreted luminal domain of the endoplasmic reticulum (ER) stress t...

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Detalles Bibliográficos
Autores principales: Chung, Kyung Min, Kim, Hyunha, Roque, Cláudio Gouveia, McCurdy, Ethan P., Nguyen, Trang T.T., Siegelin, Markus D., Hwang, Jee-Yeon, Hengst, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9623505/
https://www.ncbi.nlm.nih.gov/pubmed/36260999
http://dx.doi.org/10.1016/j.celrep.2022.111488