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On the difficulties of characterizing weak protein interactions that are critical for neurotransmitter release

The mechanism of neurotransmitter release has been extensively characterized, showing that vesicle fusion is mediated by the SNARE complex formed by syntaxin‐1, SNAP‐25 and synaptobrevin. This complex is disassembled by N‐ethylmaleimide sensitive factor (NSF) and SNAPs to recycle the SNAREs, whereas...

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Detalles Bibliográficos
Autores principales: Rizo, Josep, David, Guillaume, Fealey, Michael E., Jaczynska, Klaudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9623538/
https://www.ncbi.nlm.nih.gov/pubmed/35986639
http://dx.doi.org/10.1002/2211-5463.13473