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Variable Regions of p53 Isoforms Allosterically Hard Code DNA Interaction
[Image: see text] Allosteric regulation of protein activity pervades biology as the “second secret of life.” We have been examining the allosteric regulation and mutant reactivation of the tumor suppressor protein p53. We have found that generalizing the definition of allosteric effector to include...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9623584/ https://www.ncbi.nlm.nih.gov/pubmed/36245142 http://dx.doi.org/10.1021/acs.jpcb.2c06229 |