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Variable Regions of p53 Isoforms Allosterically Hard Code DNA Interaction

[Image: see text] Allosteric regulation of protein activity pervades biology as the “second secret of life.” We have been examining the allosteric regulation and mutant reactivation of the tumor suppressor protein p53. We have found that generalizing the definition of allosteric effector to include...

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Detalles Bibliográficos
Autores principales:	Armour-Garb, Isabel, Han, In Sub Mark, Cowan, Benjamin S., Thayer, Kelly M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9623584/ https://www.ncbi.nlm.nih.gov/pubmed/36245142 http://dx.doi.org/10.1021/acs.jpcb.2c06229

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