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Exosome biogenesis: machinery, regulation, and therapeutic implications in cancer

Exosomes are well-known key mediators of intercellular communication and contribute to various physiological and pathological processes. Their biogenesis involves four key steps, including cargo sorting, MVB formation and maturation, transport of MVBs, and MVB fusion with the plasma membrane. Each p...

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Detalles Bibliográficos
Autores principales: Han, Qing-Fang, Li, Wen-Jia, Hu, Kai-Shun, Gao, Jie, Zhai, Wen-Long, Yang, Jing-Hua, Zhang, Shui-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9623991/
https://www.ncbi.nlm.nih.gov/pubmed/36320056
http://dx.doi.org/10.1186/s12943-022-01671-0