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Exosome biogenesis: machinery, regulation, and therapeutic implications in cancer
Exosomes are well-known key mediators of intercellular communication and contribute to various physiological and pathological processes. Their biogenesis involves four key steps, including cargo sorting, MVB formation and maturation, transport of MVBs, and MVB fusion with the plasma membrane. Each p...
Autores principales: | Han, Qing-Fang, Li, Wen-Jia, Hu, Kai-Shun, Gao, Jie, Zhai, Wen-Long, Yang, Jing-Hua, Zhang, Shui-Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9623991/ https://www.ncbi.nlm.nih.gov/pubmed/36320056 http://dx.doi.org/10.1186/s12943-022-01671-0 |
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