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Thioredoxin-1 regulates self-renewal and differentiation of murine hematopoietic stem cells through p53 tumor suppressor

BACKGROUND: Thioredoxin-1 (TXN1) is one of the major cellular antioxidants in mammals and is involved in a wide range of physiological cellular responses. However, little is known about the roles and the underlying molecular mechanisms of TXN1 in the regulation of hematopoietic stem/progenitor cells...

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Detalles Bibliográficos
Autores principales: Jabbar, Shaima, Mathews, Parker, Wang, Xiaobei, Sundaramoorthy, Pasupathi, Chu, Emily, Piryani, Sadhna O., Ding, Shengli, Shen, Xiling, Doan, Phuong L., Kang, Yubin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9624023/
https://www.ncbi.nlm.nih.gov/pubmed/36316713
http://dx.doi.org/10.1186/s40164-022-00329-3