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Thioredoxin-1 regulates self-renewal and differentiation of murine hematopoietic stem cells through p53 tumor suppressor
BACKGROUND: Thioredoxin-1 (TXN1) is one of the major cellular antioxidants in mammals and is involved in a wide range of physiological cellular responses. However, little is known about the roles and the underlying molecular mechanisms of TXN1 in the regulation of hematopoietic stem/progenitor cells...
Autores principales: | Jabbar, Shaima, Mathews, Parker, Wang, Xiaobei, Sundaramoorthy, Pasupathi, Chu, Emily, Piryani, Sadhna O., Ding, Shengli, Shen, Xiling, Doan, Phuong L., Kang, Yubin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9624023/ https://www.ncbi.nlm.nih.gov/pubmed/36316713 http://dx.doi.org/10.1186/s40164-022-00329-3 |
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