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Metallothionein synthesis increased by Ninjin-yoei-to, a Kampo medicine protects neuronal death and memory loss after exposure to amyloid β(1-42)

BACKGROUND: It is possible that increased synthesis of metallothioneins (MTs), Zn(2+)-binding proteins is linked with the protective effect of Ninjin-yoei-to (NYT) on Zn(2+) toxicity ferried by amyloid β(1-42) (Aβ(1-42)). METHODS: Judging from the biological half-life (18-20 h) of MTs, the effective...

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Detalles Bibliográficos
Autores principales: Tamano, Haruna, Tokoro, Haruna, Murakami, Daichi, Tsujimoto, Rin, Nishijima, Yuka, Tsuda, Erina, Watanabe, Satoshi, Suzuki, Miki, Takeda, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9624024/
https://www.ncbi.nlm.nih.gov/pubmed/36316709
http://dx.doi.org/10.1186/s40780-022-00257-8