Supercoiling-mediated feedback rapidly couples and tunes transcription

Transcription induces a wave of DNA supercoiling, altering the binding affinity of RNA polymerases and reshaping the biochemical landscape of gene regulation. As supercoiling rapidly diffuses, transcription dynamically reshapes the regulation of proximal genes, forming a complex feedback loop. Howev...

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Detalles Bibliográficos
Autores principales: Johnstone, Christopher P., Galloway, Kate E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9624111/
https://www.ncbi.nlm.nih.gov/pubmed/36261020
http://dx.doi.org/10.1016/j.celrep.2022.111492

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9624111/
https://www.ncbi.nlm.nih.gov/pubmed/36261020
http://dx.doi.org/10.1016/j.celrep.2022.111492

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