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Immunohistochemistry with 3 different clones in anaplastic lymphoma kinase fluorescence in situ hybridization positive non-small-cell lung cancer with thymidylate synthase expression analysis: a multicentre, retrospective, Italian study

INTRODUCTION: ALK rearrangement is the only druggable oncogenic driver detectable by immunohistochemistry (IHC) not requiring further confirmation of positivity in accessing first-line specific inhibitors. ALK-positive patients experience clinical benefit from pemetrexed-based chemotherapy possibly...

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Detalles Bibliográficos
Autores principales: Bironzo, Paolo, Melocchi, Laura, Monica, Valentina, Trebeschi, Dario, Barbieri, Fausto, Maiello, Evaristo, Migliorino, Maria Rita, Lombardi, Alessandra, Tiseo, Marcello, Righi, Luisella, Graziano, Paolo, Rossi, Giulio, Novello, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pacini Editore srl 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9624140/
https://www.ncbi.nlm.nih.gov/pubmed/36083243
http://dx.doi.org/10.32074/1591-951X-756