Increased osteoclastogenesis contributes to bone loss in the Costello syndrome Hras G12V mouse model

RAS GTPases are ubiquitous GDP/GTP-binding proteins that function as molecular switches in cellular signalling and control numerous signalling pathways and biological processes. Pathogenic mutations in RAS genes severely affect cellular homeostasis, leading to cancer when occurring in somatic cells...

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Detalles Bibliográficos
Autores principales: Nandi, Sayantan, Chennappan, Saravanakkumar, Andrasch, Yannik, Fidan, Miray, Engler, Melanie, Ahmad, Mubashir, Tuckermann, Jan P., Zenker, Martin, Cirstea, Ion Cristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9624175/
https://www.ncbi.nlm.nih.gov/pubmed/36330334
http://dx.doi.org/10.3389/fcell.2022.1000575

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9624175/
https://www.ncbi.nlm.nih.gov/pubmed/36330334
http://dx.doi.org/10.3389/fcell.2022.1000575

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