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Critical Reanalysis of the Mechanisms Underlying the Cardiorenal Benefits of SGLT2 Inhibitors and Reaffirmation of the Nutrient Deprivation Signaling/Autophagy Hypothesis
SGLT2 (sodium-glucose cotransporter 2) inhibitors produce a distinctive pattern of benefits on the evolution and progression of cardiomyopathy and nephropathy, which is characterized by a reduction in oxidative and endoplasmic reticulum stress, restoration of mitochondrial health and enhanced mitoch...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Lippincott Williams & Wilkins
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9624240/ https://www.ncbi.nlm.nih.gov/pubmed/36315602 http://dx.doi.org/10.1161/CIRCULATIONAHA.122.061732 |