IMGT(®) Nomenclature of Engineered IGHG Variants Involved in Antibody Effector Properties and Formats

The constant region of the immunoglobulin (IG) or antibody heavy gamma chain is frequently engineered to modify the effector properties of the therapeutic monoclonal antibodies. These variants are classified in regards to their effects on effector functions, antibody-dependent cytotoxicity (ADCC), a...

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Detalles Bibliográficos
Autores principales: Lefranc, Marie-Paule, Lefranc, Gérard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9624366/
https://www.ncbi.nlm.nih.gov/pubmed/36278618
http://dx.doi.org/10.3390/antib11040065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9624366/
https://www.ncbi.nlm.nih.gov/pubmed/36278618
http://dx.doi.org/10.3390/antib11040065

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