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IMGT(®) Nomenclature of Engineered IGHG Variants Involved in Antibody Effector Properties and Formats
The constant region of the immunoglobulin (IG) or antibody heavy gamma chain is frequently engineered to modify the effector properties of the therapeutic monoclonal antibodies. These variants are classified in regards to their effects on effector functions, antibody-dependent cytotoxicity (ADCC), a...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9624366/ https://www.ncbi.nlm.nih.gov/pubmed/36278618 http://dx.doi.org/10.3390/antib11040065 |