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Sleep and wake cycles dynamically modulate hippocampal inhibitory synaptic plasticity

Sleep is an essential process that consolidates memories by modulating synapses through poorly understood mechanisms. Here, we report that GABAergic synapses in hippocampal CA1 pyramidal neurons undergo daily rhythmic alterations. Specifically, wake inhibits phasic inhibition, whereas it promotes to...

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Detalles Bibliográficos
Autores principales: Wu, Kunwei, Han, Wenyan, Lu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9624398/
https://www.ncbi.nlm.nih.gov/pubmed/36318572
http://dx.doi.org/10.1371/journal.pbio.3001812