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Mycn regulates intestinal development through ribosomal biogenesis in a zebrafish model of Feingold syndrome 1

Feingold syndrome type 1, caused by loss-of-function of MYCN, is characterized by varied phenotypes including esophageal and duodenal atresia. However, no adequate model exists for studying the syndrome’s pathological or molecular mechanisms, nor is there a treatment strategy. Here, we developed a z...

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Detalles Bibliográficos
Autores principales: Li, Yun-Fei, Cheng, Tao, Zhang, Ying-Jie, Fu, Xin-Xin, Mo, Jing, Zhao, Guo-Qin, Xue, Mao-Guang, Zhuo, Ding-Hao, Xing, Yan-Yi, Huang, Ying, Sun, Xiao-Zhi, Wang, Dan, Liu, Xiang, Dong, Yang, Zhu, Xiao-Sheng, He, Feng, Ma, Jun, Chen, Dong, Jin, Xi, Xu, Peng-Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9624419/
https://www.ncbi.nlm.nih.gov/pubmed/36318514
http://dx.doi.org/10.1371/journal.pbio.3001856