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ODP161 Adipose mitochondrial complex I deficiency modulates inflammation and glucose homeostasis in a sex-dependent manner

Mitochondrial dysfunction in adipose tissue has been associated with type 2 diabetes, but it is unclear whether it is a cause or the consequence. Mitochondrial complex I is a major site of reactive oxygen species generation and a therapeutic target. Here we report that genetic deletion of the comple...

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Detalles Bibliográficos
Autores principales: Yoon, John, Choi, Kyung-Mi, Ryan, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9624842/
http://dx.doi.org/10.1210/jendso/bvac150.616