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ODP161 Adipose mitochondrial complex I deficiency modulates inflammation and glucose homeostasis in a sex-dependent manner
Mitochondrial dysfunction in adipose tissue has been associated with type 2 diabetes, but it is unclear whether it is a cause or the consequence. Mitochondrial complex I is a major site of reactive oxygen species generation and a therapeutic target. Here we report that genetic deletion of the comple...
Autores principales: | Yoon, John, Choi, Kyung-Mi, Ryan, Karen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9624842/ http://dx.doi.org/10.1210/jendso/bvac150.616 |
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