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ODP007 Nephron Specific ATP6AP2 Knockout Increases Urinary Excretion of Fatty Acids while Decreasing Renal Cortical Megalin Expression

We recently reported that mice with inducible nephron specific knockout of ATP6AP2 are resistant to diet induced obesity while demonstrating significant increases in urine glucose and albumin excretion. It is not known whether urinary loss of other metabolites such as lipids contributes to impaired...

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Detalles Bibliográficos
Autores principales: Culver, Silas, Hargett, Stefan, Harris, Thurl, Siragy, Helmy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9624863/
http://dx.doi.org/10.1210/jendso/bvac150.021