PSUN304 CRN04777 an Oral, Nonpeptide SST5-selective Somatostatin Agonist Dose Dependently Suppresses Basal and Stimulated Insulin Secretion

Congenital hyperinsulinism (HI) is the most common cause of persistent hypoglycemia in neonates, infants, and children, and is caused by genetic mutations in the insulin secretion pathway in pancreatic beta-cells. Current medical and surgical treatments are often highly burdensome, only partially ef...

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Detalles Bibliográficos
Autores principales: Ferrara-Cook, Christine, Luo, Rosa, De La Torre, Eduardo, Wang, Yang, Betz, Stephen, Madan, Ajay, Struthers, Scott, Hövelmann, Ulrike, Heise, Tim, Krasner, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Diabetes & Glucose Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9624917/
http://dx.doi.org/10.1210/jendso/bvac150.850

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9624917/
http://dx.doi.org/10.1210/jendso/bvac150.850

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