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ODP145 Epigenesis of 11beta-hydroxysteroid dehydrogenase 1 in the adipose tissue of aldosterone-producing adenoma

OBJECTIVE: 11Beta-hydroxysteroid dehydrogenase 1 (11beta-HSD1) is the key enzyme of metabolic syndrome. The transcript-specific epigenetic regulation of 11b-HSD1 (HSD11B1) is reported. We examined the HSD11B1 mRNA level and methylation status of the promoter region of the HSD11B1 in the adipose tiss...

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Detalles Bibliográficos
Autores principales: Aono, Daisuke, Demura, Masashi, Karashima, Shigehiro, Kometani, Mitsuhiro, Konishi, Seigo, Sawamura, Takashi, Takeda, Yoshimichi, Takeda, Yoshiyu, Yoneda, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9624918/
http://dx.doi.org/10.1210/jendso/bvac150.495