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ODP145 Epigenesis of 11beta-hydroxysteroid dehydrogenase 1 in the adipose tissue of aldosterone-producing adenoma
OBJECTIVE: 11Beta-hydroxysteroid dehydrogenase 1 (11beta-HSD1) is the key enzyme of metabolic syndrome. The transcript-specific epigenetic regulation of 11b-HSD1 (HSD11B1) is reported. We examined the HSD11B1 mRNA level and methylation status of the promoter region of the HSD11B1 in the adipose tiss...
Autores principales: | Aono, Daisuke, Demura, Masashi, Karashima, Shigehiro, Kometani, Mitsuhiro, Konishi, Seigo, Sawamura, Takashi, Takeda, Yoshimichi, Takeda, Yoshiyu, Yoneda, Takashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9624918/ http://dx.doi.org/10.1210/jendso/bvac150.495 |
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