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OR24-5 Zebrafish in Utero Glucose Exposure Induces Lipid Dysregulation That Is Abrogated by Acetyl CoA Carboxylase or Glycolysis Inhibition

BACKGROUND AND AIM: One in ten pregnancies suffer from Gestational Diabetes Mellitus (GDM). GDM exposes fetus to high uterine glucose that causes fetal hyperglycemia. At birth Fetal hyperglycemia results in hypoglycemia, macrosomia, and larger than normal infants and these infants are predisposed to...

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Detalles Bibliográficos
Autores principales: Cox, Carol, Gibert, Yann, Speed, Joshua, Konadu, Bridget
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9624971/
http://dx.doi.org/10.1210/jendso/bvac150.733