RF21 | PSAT76 Epigenetic Programs Stabilize a Differentiated Cell State Required for Sustained Proliferation in Adrenocortical Carcinoma

Adrenocortical carcinoma (ACC) is a rare, aggressive, and poorly understood cancer of the adrenal cortex. Abnormal epigenetic patterning is a major predictor of dismal disease outcomes. Patients with genome-wide CpG island hypermethylation (CIMP-high) experience rapidly recurrent and routinely fatal...

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Detalles Bibliográficos
Autores principales: Mohan, Dipika, Borges, Kleiton, Finco, Isabella, LaPensee, Christopher, Rege, Juilee, Little, Donald, Else, Tobias, Almeida, Madson, Latronico, Ana Claudia, Mendonca, Berenice, Auchus, Richard, Rainey, William, Marie, Suely, Giordano, Thomas, Venneti, Sriram, Candida Fragoso, Maria, Breault, David, Lerario, Antonio, Hammer, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Adrenal
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9625053/
http://dx.doi.org/10.1210/jendso/bvac150.277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9625053/
http://dx.doi.org/10.1210/jendso/bvac150.277

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