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Alternative splicing of apoptosis genes promotes human T cell survival

Alternative splicing occurs in the vast majority of human genes, giving rise to distinct mRNA and protein isoforms. We, and others, have previously identified hundreds of genes that change their isoform expression upon T cell activation via alternative splicing; however, how these changes link activ...

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Detalles Bibliográficos
Autores principales: Blake, Davia, Radens, Caleb M, Ferretti, Max B, Gazzara, Matthew R, Lynch, Kristen W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9625086/
https://www.ncbi.nlm.nih.gov/pubmed/36264057
http://dx.doi.org/10.7554/eLife.80953