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PMON163 Effect of Osilodrostat on Androgens and Adrenal Hormones in Patients With Cushing's Disease: Long-Term Findings From the Phase III, Prospective LINC 3 Study

INTRODUCTION: Osilodrostat decreases cortisol production by inhibiting 11β-hydroxylase, which increases adrenal hormones proximal to the blockade. Here, we describe these effects of osilodrostat and associated adverse events (AEs). The efficacy and safety of osilodrostat in patients with Cushing...

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Detalles Bibliográficos
Autores principales: Fleseriu, Maria, Biller, Beverly M K, Shimatsu, Akira, Newell-Price, John, Tabarin, Antoine, Vila, Greisa, Piacentini, Andrea, Pedroncelli, Alberto M, Pivonello, Rosario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9625140/
http://dx.doi.org/10.1210/jendso/bvac150.1136