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ODP338 Neuromedin B Receptor Antagonist Suppresses ACTH Secretion and Cell Proliferation in Human and Mouse Corticotroph Adenoma

OBJECTIVE: We previously reported that Neuromedin B (NMB) is expressed in murine pituitary corticotrophs under adrenal insufficiency (1). Because NMB is also expressed in several cancer cells and stimulates ACTH secretion, we hypothesized that NMB is related to corticotroph adenoma cell proliferatio...

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Detalles Bibliográficos
Autores principales: Atsumi, Tatsuya, Sekizaki, Tomonori, Kameda, Hiraku, Nakamura, Akinobu, Miya, Aika, Nomoto, Hiroshi, Yong Cho, Kyu, Motegi, Hiroaki, Miyoshi, Hideaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9625167/
http://dx.doi.org/10.1210/jendso/bvac150.1047