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RF04 | PSUN233 Design of an Ultra-Stable Insulin/Glucagon Fusion Protein

Insulin replacement therapy is lifesaving for insulin-dependent diabetic patients, but it comes with an ever-present threat of hypoglycemia, which can eventually cause ischemic events, arrhythmias, neurological damage, coma, or even death. Consequently, the risk of hypoglycemia remains the most sign...

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Detalles Bibliográficos
Autores principales: Grabowski, Rachel, Ismail-Beigi, Faramarz, Jarosinski, Mark, Phillips, Nelson, Poordian, Shayan, Varas, Nicolas, Weiss, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9625213/
http://dx.doi.org/10.1210/jendso/bvac150.870