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PMON210 Ovariectomy of Middle-Aged Female Mice Leads to Decreased Fat Oxidation and Energy Expenditure Accompanied by Weight Gain and Dysregulated Blood Glucose

INTRODUCTION: In humans, menopause brings upon total body weight gain with increased visceral adiposity and a resulting increase in cardiometabolic risk profile. Although well described, the specific sequence and underlying mechanisms for this remain elusive. Rodent ovariectomy (OVX) is routinely us...

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Detalles Bibliográficos
Autores principales: Stokar, Joshua, Gurt, Irina, Lishinsky, Natan, Offir, Neta, Dresner-Pollak, Rivka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9625300/
http://dx.doi.org/10.1210/jendso/bvac150.1420