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PMON275 GONAD-on-CHIP to study early gonad development and DSD

During embryonic development, mutually antagonistic signaling cascades determine the fate of the bipotential gonad towards a testicular or ovarian identity. Errors in this process result in human Disorders of Sex Development (DSDs), where there is discordance between chromosomal, gonadal, and anatom...

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Detalles Bibliográficos
Autores principales: Bashamboo, Anu, Gonen, Nitzan, Eozenou, Caroline, Mitter, Richard, Bernardo, Andreia Sofia, Chervova, Almira Chervova, Frachon, Emmanuel, Commère, Pierre-Henri, Brailly-Tabard, Sylvie, Mazen, Inas, Gobaa, Samy, Smith, James, McElreavey, Kenneth, Lovell-Badge, Robin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9625342/
http://dx.doi.org/10.1210/jendso/bvac150.1454