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RF03 | PMON302 A Unique Estrogen-Sensitive Fibroblast Population Drives Abdominal Muscle Fibrosis

 : Weakening of the lower abdominal wall muscle via fibrosis causes visceral contents to bulge out, forming inguinal hernias. Humanized aromatase (Aromhum) transgenic male mice develop this weakness in the lower abdominal muscle (LAM) tissue, characterized by extensive fibrosis, muscle atrophy, and...

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Detalles Bibliográficos
Autores principales: Potluri, Tanvi, Taylor, Matthew, Stulberg, Jonah, Lieber, Richard, Zhao, Hong, Bulun, Serdar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9625530/
http://dx.doi.org/10.1210/jendso/bvac150.1512