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PMON69 Effective Suppression of Gonadotropins and Gonadal Steroids Following Oral Administration of Leuprolide

A platform designed to enable systemic delivery of peptides via the oral-GI route was employed to deliver low doses of leuprolide --- 4 mg qd (Treatment A, n=9), 4 mg bid (Treatment B, n=9), and 10 mg bid (Treatment D, n=12) --- daily for 28 days to regularly-menstruating, healthy female volunteers....

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Detalles Bibliográficos
Autores principales: Shangold, Gary, Rubin, Arkady, Daggs, Thomas, Vrettos, John, Rasums, Andrejs, Consalvo, Angelo, Skeet, Nicola, Shields, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9625566/
http://dx.doi.org/10.1210/jendso/bvac150.1165