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OR25-3 Sperm-carried IGF2 Downregulates Mitogens Released by Sertoli Cells: A Paracrine Mechanism of Spermatogenetic Regulation?

The presence of insulin-like growth factor 2 (IGF2) mRNA has been demonstrated in human and mouse spermatozoa. However, the expression of the IGF2 protein in spermatozoa and its function is not known. To accomplish this, we searched for IGF2 protein in spermatozoa of four healthy Caucasian men by We...

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Detalles Bibliográficos
Autores principales: Arato, Iva, Bellucci, Catia, Calogero, Aldo, Condorelli, Rosita, La Vignera, Sandro, Luca, Giovanni, Mancuso, Francesca, Cannarella, Rossella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9625571/
http://dx.doi.org/10.1210/jendso/bvac150.1412